Gene Arrays Services

• Image analysis to identify individual clusters of reads
• At each cycle of the sequencing run, using the relative intensity levels at each cluster to perform Base-Calling
• Generation of sequence reads with associated quality scores for each base
• Generation of filtered read data, based on the per-base quality scores
• Generation of a customised Pipeline report, summarising run statistics and quality control analysis

Advanced Bioinformatic Analysis

Alignment to Reference Sequence

• Mapping of all reads to a specified reference genome
• Statistic report detailing coverage, orientation of mapped reads, and numbers of unmapped reads
• Summary of coverage available in both graphical and tabular format

Visualizing sequence data within a genome browser

Re-sequencing and polymorphism detection

• Mutation detection in samples
• Novel mutation discoveries
• Annotation of sequence polymorphisms
• Functional analysis of target genes

ChIP Sequencing

• ChIP-seq analysis to determine genomic regions and peaks
• Annotation of ChIP-seq regions and Peaks
• Sequence motif analysis
• Functional analyses of ChIP-seq target genes

RNA Sequencing

• Identification of exon splice crossing sequencing reads
• Identification of the differences in gene expression between the control and treated samples
• Identification of the differences in alternative splicing between the control and treated samples
• Full gene annotation

Small RNA Sequencing